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BioTechCircle News®

January 2012

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Issue 103 Part b

Starting in January 2012, you will find links to our 4-part monthly report issues at Bioreports. All previous issues through December 2011 continue to be archived HERE.

In this articles section: links to 73 free Web articles in 15 major categories. Click on the category list below to go immediately to that section. (Part b continues our original classifications, with links to articles on research advances and other areas that have longer-range impact.)

The major categories below are further subdivided to make it easy for you to locate
news and technology developments, the business and the markets in the life sciences
of particular interest to you. The brief synopses will help you decide which articles you'd
like to read. Simply click on the article's title to go directly to the original article.

Here are this month's major categories:

Agri-Biotech (15 articles)
Biobusiness Management (5 articles)
Clinical Trials (2 articles)
Diagnostic Tools (1 article)
Industry (12 articles)
Investments/Government Support (4 articles)
Novel Applications (3 articles)
Organizations (1 article)
People Profiles (1 article)
Personalized Medicine (1 article)
Pharmaceuticals (1 article)
Platform Technologies (8 articles)
Research Advancements (17 articles)
Research Tools (1 article)
Strategic Relationships (1 article)

For a brief explanation of how we categorize the articles, please see "Express Guilde to Monthly Web Articles."

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   	AGRI-BIOTECH

	Subcategory: Animal

	World's Smallest Frog Discovered
	          Richard Black BBC News (11-Jan-12)
	A frog species that appears to be the world's smallest has been discovered in 
	Papua New Guinea. The tiny frog sits easily on a US dime, whose diameter is 
	18mm.
	
	Carbon Dioxide Is "Driving Fish Crazy"
	          Coral Reef Studies (16-Jan-12)
	Rising human carbon dioxide emissions may be affecting the brains and central
	 nervous system of sea fishes with serious consequences for their survival, 
	interfering with fishes’ ability to hear, smell, turn and evade predators
	
	Subcategory: Crops

	Researchers Discover 'Nourishing Gene' in Maize
	          Gemma Mackenzie Farmers Weekly (15-Jan-12)
	A gene, named Meg1, regulates the optimum amount of nutrients flowing 
	from mother to offspring in maize plants. This imprinting gene expression 
	also occurs in human genes, but this is the first time a similar gene is found in 
	the plant world.
	
	Don't Ignore Benefits of GM, Says Chief Scientist 
	          Philip Case	Farmers Weekly	(23-Jan-12)
	More than one trillion meals have been made using GM crops in North 
	America and there has not been a single case in the law courts of anyone suing 
	after eating GM products, says UK biologist and government advisor.

	Call to Arms
	          Howard Hughes Medical Institute (22-Jan-12)
	When pathogens invade, plant growth must be temporarily slowed while the 
	plant turns its genetic resources  to fortifying its defenses. A molecular master
	switch triggers this genetic overhaul, altering the activity of as many as 3,000
        different genes.

	Subcategory: Energy/ Fuel

	Custom-mutated Bacteria Converts Seaweed to Fuel
	          Wynne Parry The Christian Scientist (19-Jan-12)
	Bacteria, genetically engineered to break down a previously inaccessible sugar 
	in seaweed, called alginate, can convert brown seaweed into biofuel. Opens up
	a new possible source of energy that could help replace fossil fuels, like 
	gasoline.
	
	Subcategory: Environment

	Agbiotech Is Working to Help Plants Cope with Global Warming
	          John Sterling Genetic Engineering & Biotechnology News (18-Jan-12)
	Plant and Animal Genome Conference indicates development of 
	climate-resilient crop varieties with growth plasticity, resistance to biotic and 
	abiotic stresses, improved growth and development patterns is important to 
	combat climate change.
	
	Amazing Map Shows Every Tree in the United States
	          Diane Pham Inhabitat (17-Jan-12)
	Based on a series of data sources including readings collected from 
	space-based radars, satellite sensors, computer models, and simply counting 
	trees, map was created to help determine how the world’s forests have the 
	potential to store more carbon.
	
	The Changing Amazon
	          Nature	(01-Jan-12)
	The United Nations Conference on Sustainable Development will discuss how
	 to protect the Amazon, Earth's largest rainforest; a proposed change to 
	Brazil's forest code could speed the destruction of this biodiversity hot spot. 
	Links to other articles.
	
	Ocean Acidification Study Reveals Effects of Carbon Dioxide
	          R & D Magazine (25-Jan-12)
	Might a penguin's next meal be affected by the exhaust from your tailpipe? 
	The answer may be yes, when you add your exhaust fumes to the total 
	amount of carbon dioxide lofted into the atmosphere by humans since the 
	industrial revolution.
	
	Subcategory: Food

	Bill Gates Defends High-Tech Agriculture
	          Donna Gordon Blankinship ChemInfo (25-Jan-12)
	Response to criticism that the high-tech solutions Gates advocates for world 
	hunger are too expensive or bad for the environment: Countries can embrace 
	modern seed technology and genetic modification or their citizens will starve.
	
	Guest Post: Sustainable Agriculture and Food Demand, by Tim Benton
	          Tim Benton	Seed, Feed and Food (11-Jan-12)
	Without investing in soils, reducing carbon impacts, ensuring lower pollution 
	levels, preserving ecosystem functions of many sorts, agriculture will 
	eventually splutter and die, becoming untenable, Benton says.
	
	Subcategory: Immunology/ Infectious Diseases

	Stinky Frogs Are a Treasure Trove of Antibiotic Substances
	          R & D Magazine (25-Jan-12)
	Frogs live in warm, wet places where bacteria thrive and have adapted skin 
	that secretes chemicals, known as peptides, to protect themselves from 
	infections.
	
	Subcategory: Microorganisms

	Fungi Discovered In The Amazon Will Eat Your Plastic
	          FastCo.Exist (31-Jan-12)
	Polyurethane seemed like it couldn’t interact with the earth’s normal 
	processes of breaking down and recycling material. That’s just because it 
	hadn’t met the right mushroom yet.
	
	Subcategory: Miscellaneous

	Amid Drought, Water Desalination Gets Attractive
	          Juan Carlos Llorca Manufacturing.net (04-Jan-12)
	Desalination is the only option Texas has for bringing "new water" to the 
	state's supply as the readily available fresh water in aquifers and reservoirs is 
	used up. Expected to produce nearly 310,000 acre-feet (~ 101 bil gal) of 
	drinkable water by 2060.

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	BIOBUSINESS MANAGEMENT

	Subcategory: Education

	An Early Start on Innovation
	          Lindsay Hock R & D Magazine (15-Dec-11)
	A lack of students going into STEM (science, technology, engineering, 
	mathematics ) fields not only affects the learning curves in schools, but it also 
	affects our global competitiveness and our ability as a nation to innovate, say 
	experts.
	
	Subcategory: Government/ Approvals

	Meeting the Need for Speed
	          Kimberley Sirk Drug Discovery News	(01-Jan-12)
	Describes TREAT (Transforming the Regulatory Environment to Accelerate 
	Access to Treatments) proposal to streamline and better organize the way 
	that potential drugs come to market.
	
	Subcategory: Miscellaneous

	The Rise of the Biobased Economy... And Why Brand Owners Need to Develop a 
	Strategy in 2012
	          Jacquelyn Ottman and Mark Eisen Huffington Post (18-Jan-12)
	The USDA Certified Biobased label is part of a federal BioPreferred program 
	designed to help grow "green" jobs, stimulate the rural economy, promote 
	energy independence, and prompt a shift to renewable resources from 
	petroleum.
	
	Subcategory: Mobile Medicine

	Going Paperless: The Digital Lab
	          Jim Giles	Nature	25-Jan-12
	Lab-management software and electronic notebooks are here — and this time, 
	it's more than just talk, writes Giles. Most early notebook-software programs 
	had limited impact, often because they weren't easy enough to use.
	
	Subcategory: Patent/Intellectual Property Issues

	Worldwide Patent Filings and Grants on the Rise
	          Technology Transfer Tactics	(25-Jan-12)
	US, Japan and Germany are top 3 European patent filers, top 3 companies 
	receiving US patents were IBM, Samsung and Canon. The only life sciences 
	company making the list was E I Du Pont de Nemours & Co. Tables and 
	links.

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	 CLINICAL TRIALS

	Subcategory: Miscellaneous

	Clinical Trials Remain Unpublished
	          Ansa Varughese	BioTechniques (18-Jan-12)
	Of 635 completed clinical trials funded by the National Institutes of Health 
	(NIH), less than half of the results were published within 30 months of 
	completion. “It’s wasteful and inefficient...not respectful for the patients 
	enrolling in these trials.”
	
	Subcategory: Subject Enrollment/Management

	Therapy Dose Management During Clinical Development of Oncology Products
	          Salvatore J. Salamone, et al. Drug Discovery & Development (24-Jan-12)
	How many drugs have failed in clinical trials because the pharmacokinetic 
	variability was such that the incorrect dose was administered to some 
	patients, or how many trials had to recruit a larger number of patients because
	of exposure variability?
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	DIAGNOSTIC TOOLS

	Subcategory: Microorganisms

	Blinking Bacteria Warn of Contamination | Video
	          Ashley Yeager BioTechniques	 (20-Jan-12)
	The ability to coordinate bacteria behavior in response to changes in their 
	environment could improve bioelectrical devices that detect contamination in 
	water, food, and other important resources.
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	INDUSTRY

	Subcategory: Bio Pharma

	Declaration of Independence
	          Adelene Q. Perkins Genetic Engineering & Biotechnology News (15-Jan-12)
	Perkins believes the impact and success of the biotech industry is clear. 
	Biotech has tackled some of the most difficult and enigmatic problems and 
	diseases, and we have discovered and delivered highly effective therapies.
	
	US Pharma: 282 Meds for Children Now in R&D
	          Lynne Taylor Pharma Times (13-Jan-12)
	Children and adolescents have unique health care needs. Drugs in development 
	include 54 potential new treatments for cancer, 49 for infectious diseases, 48 
	for genetic disorders, 25 for neurological disorders.
	
	Survey: Lack of Funds, Regulatory Climate Threaten Biomedical Industry
	          Michael Christel R&D Directions (13-Jan-12)
	Survey of a newly released survey of CEOs from life sciences companies in 
	California, the largest biomedical cluster in the world, reports the 3 biggest 
	threats: access to capital, the regulatory environment, lack of 
	innovation/productivity in R&D.
	
	Subcategory: Biomanufacturing

	Bioprocessors Enter Year on Optimistic Note
	          Eric S. Langer Genetic Engineering & Biotechnology News (15-Jan-12)
	The biopharmaceutical manufacturing sector may be even more 
	recession-resistant than other healthcare areas. Budget estimates for 2012 are, 
	once again, up strongly for acquisition of new technologies, capital equipment,
	and training.
	
	Subcategory: Environment

	Scientists Say Cut Soot, Methane to Curb Warming
	          Seth Borenstein	R & D Magazine (13-Jan-12)
	Stop focusing so much on carbon dioxide, say scientists. Reducing methane 
	and soot offers quicker fixes, and dramatically cutting soot with existing 
	technology would save between 700,000 and 4.7 million lives each year.
	
	Subcategory: Geographic Focus

	The Top 10 Smart Cities on the Planet
	          Boyd Cohen Co.Exist (01-Jan-12)
	These smart cities use information and communication technologies (ICT) to 
	be more intelligent, efficient in the use of resources; resulting in cost and 
	energy savings;,improved service delivery and quality of life, reduced 
	environmental footprint.
	
	Subcategory: Imaging

	Best Science Multimedia of 2011
	          Cristina Luiggi The Scientist (23-Dec-11)
	A look at this year’s most memorable science videos, images, and websites, 
	including Nikon’s 2011 Small World Competition, Wellcome Image awards 
	2011 and Science Prize for Online Resources in Education (SPORE).
	
	Subcategory: Market Research

	2011 Review and Outlook for Biotechnology in 2012
	          Life Science Digest (25-Jan-12)
	Reviews new drug approvals, pipeline and R&D investment, access to capital,
	other issues. Tables: top 10 gainers/decliners  from NASDAQ Biotech Index. 
	Chart.
	
	Subcategory: Miscellaneous

	GE Global Innovation Barometer
	          GE Global Innovation (01-Jan-12)
	Links to press release; full data set; global results report; Milken Institute's 
	country innovation profiles with country by country comparisons; country 
	pages; macroeconomic perspectives on global trends in innovation.
	
	Report Suggests How to Strengthen U.S. Competitiveness
	          Laboratory Equipment (24-Jan-12)
	Summaraizes key findings of U.S. Department of Commerce related to basic 
	research, education, infrastructure, manufacturing. Link to full report.
	
	Science and Engineering Indicators 2012
	          National Science Board (01-Jan-12)
	Links to a wealth of information on science and engineering in education, the 
	work force academia, society and trends. Data on individual U.S. states; 
	figures, tables, slides, appendices.
	
	American Innovation: Nope, Not Dead Yet
	          The Atlantic (18-Jan-12)
	New report from the National Science Board says that when it comes to high 
	tech industries, the U.S. is still by far the global leader. Refutes the common 
	belief that loss of high-tech manufacturing jobs to Asia equates to loss of 
	innovation leadership.
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	 INVESTMENTS/ GOV. SUPPORT

	Subcategory: Miscellaneous

	Cap in Hand
	          Nature	(18-Jan-12)
	Academic researchers are increasingly turning to private funders and wealthy 
	individuals- turned-philanthropists to pay for their work. Links to stories 
	ranging from funding by billionaires to crowd-funding.
	
	Subcategory: Personalized Medicine

	Genes that Fit Everyone
	          Kimberly Sirk Drug Discovery News (01-Jan-12)
	The U.S. National Institutes of Health (NIH) has committed close to half a 
	billion dollars toward supporting newer and faster gene sequencing efforts. 
	Allows exploration of the front edge of genomics, which will move into 
	genomic medicine.
	
	Subcategory: Research Labs
	World-Class Scientists Chosen for HHMI’s First International Early Career 
	Award
	          Howard Hughes Medical Institute (24-Jan-12)
	Top biomedical scientists from 12 countries will be integrated into HHMI’s 
	scientific community, attending meetings and giving talks to HHMI’s 
	investigators and early career scientists. The 28 recipients represent a wide 
	range of disciplines.
	
	Subcategory: Venture

	Growth of Corporate Ventures Reflected in Rising VC Numbers	
	          Genetic Engineering & Biotechnology News (24-Jan-12)
	Despite the continued drop in first-sequence investments, fourth-quarter and 
	full-year 2011 venture capital numbers for biotechnology showed significant 
	gains, thanks in part to the rise of corporate venture funds.
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	NOVEL APPLICATIONS

	Subcategory: Energy/ Fuel

	Project to Pour Water into Volcano to Make Power
	          Jeff Barnard ChemInfo (14-Jan-12)
	Scientists hope the water pumped into the side of a dormant volcano comes 
	back to the surface fast enough and hot enough to create cheap, clean 
	electricity that isn't dependent on sunny skies or stiff breezes.
	
	Subcategory: Environment

	Bristol Scientists Produce World's Frst Magnetic Soap
	          University of Bristol (23-Jan-12)
	Iron, dissolved in liquid surfactant to create a soap that can be controlled by 
	magnets, could be used to create cleaning products that can be removed after 
	application and used in the recovery of oil spills at sea.
	
	Subcategory: Miscellaneous

	Researchers Find Speed Limit for Birds—and Drones
	          R & D Magazine (19-Jan-12)
	Given a certain density of obstacles, there is a speed below which a bird and 
	any other flying object has a fair chance of flying collision-free. Any faster, 
	and a bird or aircraft is sure to smack into something, no matter how much 
	information it has.
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	ORGANIZATIONS

	Subcategory: Environment

	American Picker
	          Chris Fox Manufacturing.net	 (06-Jan-12)
	A company based on the reuse of waste materials has a growing list of 
	repurposed materials, such as marketing old billboard vinyls as robust, 
	water-proof tarps. In many ways their products are often better than some of 
	new made-for materials.
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	PEOPLE PROFILES

	Subcategory: Miscellaneous

	Top People of 2011
	          Jef Akst The Scientist (21-Dec-11)
	Magazine recounts the year’s top science prize winners and top-notch 
	scientists that passed away. Includes nobelists, protein folding pioneers, the 
	MacArthur Five. Links to in-depth articles in each category.
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	PERSONALIZED MEDICINE

	Subcategory: Geographic Focus

	Norway Launches National Cancer Genomic Medicine Effort
	          GenomeWeb Daily News	 (20-Jan-12)
	Objectives include: provide a national network for implementation of 
	personalized cancer medicine in Norway, establish a nationwide cancer 
	mutation database in collaboration with the Cancer Registry.
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	PHARMACEUTICALS

	Subcategory: Materials

	Bridge Made From Recycled Plastic Bottles
	          Ann R. Thryft DesignNews (09-Jan-12)
	Recycled Structural Composite (RSC), a proprietary composite thermoplastic
	material is made from 100% recycled plastics. It's 100% recyclable at the end 
	of its useful life, won't rot, crumble, splinter, rust, or corrode. No painting, 
	maintenance.
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	PLATFORM TECHNOLOGIES

	Subcategory: Cell Therapy

	Waste not, Want not
	          Kelsey Kaustinen Drug Discovery News (01-Jan-12)
	Describes a new, $840,000, three-year collaboration aiming at using umbilical 
	cord blood as a source of blood-forming stem cells to treat patients with 
	diseases such as leukemia, lymphoma, myeloma or sickle cell anemia.
	
	Umbilical Cord Stem Cells That Yield Brain Cells
	          Zee News (18-Jan-12)
	Scientists have for the first time transformed stem cells from umbilical cords 
	into other types of cells, which may have several therapeutic applications for 
	spinal cord injuries and multiple sclerosis, among other nervous system 
	diseases.

	Subcategory: Genomics

	Expanding the Genomic Map
	          Riken Research	(27-Jan-12)
	Newly identified genetic variants could provide useful biomarkers for 
	predicting and treating metabolic disorders in East Asian individuals. Most 
	genome-wide association studies (GWAS) have focused on populations of 
	European ancestry.

	Subcategory: Materials

	Breakthrough in Bid to Grow Blood Vessels in the Lab which Could Revolutionize 
	Heart Attack and Stroke Treatment
	          Tamara Cohen Daily Mail (15-Jan-12)
	Researchers use patients’ own skin cells to make different types of vascular 
	smooth muscle cells. Could help create blood vessels in the laboratory for 
	surgeons simply to implant into patients – as an alternative to heart bypass 
	treatment and stenting.
	
	Artificial Living Tissue Could Come from a Printer
	          Laboratory Equipment (17-Jan-12)
	Scientists are working on creating artificial living tissues using a very special 
	kind of inkjet printer. Still in its initial stages, this technology could 
	nonetheless soon provide biological samples that could be used for testing 
	new drugs.
	
	Bits of Life, Drop by Drop
	          R & D Magazine (16-Jan-12)
	Scientists are working on a technique that should eventually allow them to 
	"print" living constructs resembling human tissues. Could be used as models 
	for testing new drugs, reduce the need for animal testing.
	
	Subcategory: Microorganisms

	Hardy Bacteria Help Make Case for Life in the Extreme
	          Penn State Live	(30-Jan-12)
	Respiration in Chryseobacterium and Paenisporosarcina is found to occur at 
	temperatures ranging from -27F to +24F. May have implications for the 
	search for life on other planets, like Mars.
	
	Genetics Study Reveals how Bacteria behind Serious Childhood Diseases Evolve 
	to Evade Vaccines
	          Wellcome Trust	(30-Jan-12)
	Bacteria evading the vaccine swap the region of the genome responsible for 
	making the polysaccharide coating with the same region from a different 
	serotype, not targeted by the vaccine. This effectively makes the bacteria 
	invisible to the vaccine.
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	RESEARCH ADVANCEMENTS

	Subcategory: Addiction

	Study Offers Clue As to Why Alcohol is Addicting
	          Bioscience Technology (17-Jan-12)
	Endorphin release in the nucleus accumbens and orbitofrontal cortex in 
	response to alcohol consumption has been directly observed in humans for the
	first time. Provides a possible target for developing more effective drugs for 
	treatment.
	
	Don’t Stress Out
	          Kelsey Kaustinen Drug Discovery News (10-Jan-12)
	Scientists have discovered an endogenous anti-stress peptide in the brain that 
	is capable of preventing and even reversing some of the cellular effects of 
	alcohol dependence.
	
	Subcategory: Disease Prevention

	Antimicrobial Scrubs May Decrease Bacterial Burden
	          Drug Discovery & Development (20-Jan-12)
	Use of antimicrobial impregnated scrubs plus good hand hygiene is effective in
	 reducing methicillin-resistant Staphylococcus aureus (MRSA) on health care 
	workers’ apparel; may play a role in decreasing the risk of MRSA 
	transmission to patients.

	Subcategory: Immunology/ Infectious Diseases

	Alternative Therapy Approach for Hepatitis C
	          Drug Discovery & Development (17-Jan-12)
	The HCV is constantly mutating, making it difficult to develop antiviral 
	therapies that target the virus itself. A new inhibitor decreases the size of host
	fat droplets in liver cells and stops HCV from multiplying and infecting other
	cells.
	
	Cardiff University, King's College Uncover Diabetes Discovery
	          Drug Discovery & Development (16-Jan-12)
	Research shows how killer T cells might play an important role in 
	autoimmune diseases like diabetes. In the future, at risk groups could be 
	identified and treated earlier.
	
	Powerful Drug's Surprising, Simple Method could Lead to Better Treatments
	          Liz Ahlberg	University of Illinois	(17-Jan-12)
	Top drug for treating systemic fungal infections works by simply binding to a
	lipid molecule essential to yeast’s physiology. Finding could lead to better 
	treatment for microbial infections and diseases caused by ion channel 
	deficiencies.
	
	Feature: A Delicate Balance - Investigating Intestinal Inflammation
	          Michael Regnier	 Wellcome Trust	(31-Jan-12)
	Professor Fiona Powrie, the 2012 Louis-Jeantet Prize for Medicine awardee 
	discusses research showing that the immune system's cells and signals do 
	different things according to where they are located.
	
	Subcategory: Metabolism: Obesity, Diabetes

	‘Killer Cells’ and Diabetes
	          Bioscience Technology (16-Jan-12)
	Killer T-cells in the human body which help protect us from disease can 
	inadvertently destroy cells that produce insulin. Study provides the first 
	evidence of this mechanism in action, could offer new understanding of the 
	cause of Type 1 diabetes.

	Minnesota Researchers on the Cusp of a Diabetes Cure
	          Lorna Benson Minnesota Public Radio (17-Jan-12)
	People with diabetes have lost their insulin cells or they don't work properly. 
	With genetic characteristics that are remarkably similar to humans, pigs may 
	hold the cure to this disease which has become a worldwide epidemic.
	
	Subcategory: Miscellaneous

	Cells Dispose of 'Garbage' in Cyclic Waves
	          Bioscience Technology (25-Jan-12)
	Tens of billions of cells die daily in the human body and taking out the garbage
	(getting rid of the dead cells) is critical to health. Discusses the intricately 
	choreographed ballet that involves both the cells’ encapsulation and 
	degradation.
	
	Out of Order: Gift Horses
	          Randall C. Willis Drug Discovery News (01-Jan-12)
	In the past, the pharmaceutical industry has figured out how to make money 
	from tree barks and saps, citrus mold and other natural products. Surely we 
	can figure out how to take advantage of the untapped knowledge of 
	non-Western medicine, writes Willis.

	Subcategory: Oncology

	Study Shows How A Group of Tumor Cells Prevent Cancer Spread
	          Bioscience Technology (17-Jan-12)
	Anti-angiogenic therapies, which shrink cancer by cutting off tumors’ blood 
	supply, may be inadvertently making tumors more aggressive and likely to 
	spread. Pericytes, however, are found to inhibit tumor growth
	
	Agent May Suppress Brain Metastasis
	          Drug Discovery & Development (18-Jan-12)
	Brain metastases are increasing and are often a primary reason patients with 
	breast cancer do not survive, say researchers. Pigment epithelium-derived 
	factor (PEDF), studied for therapy on macular degeneration, may treat brain 
	cancer metastasis.
	
	Examining Recent Approaches to Treating Solid Tumors
	          Punit Dhillon Drug Discovery News (01-Jan-12)
	Treatment of solid-tumor cancers, ranging from melanoma and Merkel cell 
	carcinoma to cutaneous T-cell lymphoma, continues to be a major challenge 

	Studies Show Pancreatic Cancer Starts to Spread Before Initial Tumor Is Evident 
	          Genetic Engineering & Biotechnology News (19-Jan-12)
	A fluorescent cell tagging system demonstrates in a mouse model that 
	pancreatic cancer cells begin to spread out and move to other tissue sites well 
	before the initial tumor is clinically evident.
	
	Subcategory: Pain Management

	New "Omics" Technique Taps into Unknown Metabolome
	          Janelle Weaver BioTechniques (23-Jan-12)
	A novel potential drug target for the treatment of chronic pain has been 
	revealed by untargeted metabolomics. Untargeted metabolomics allows 
	scientists to analyze thousands of metabolites in an unbiased manner.
	
	Subcategory: Pediatrics/ Neonatology

	First Studies in Pediatric Cancer Genome Project Identify Genetic Changes in 
	Leukemia, Retinoblastoma
	          Amy Swinderman Drug Discovery News (24-Jan-12)
	Researchers have published the first of many studies expected to be released 
	in 2012 that are part of the Pediatric Cancer Genome Project (PCGP) that 
	aims to identify the genetic changes associated with some of the deadliest 
	forms of childhood cancer.
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	RESEARCH TOOLS

	Subcategory: Mobile Medicine

	Technological Healing
	          Sharon Begley Technology Review (01-Jan-12)
	Does turning the flow of data into a deluge lead to better results on a large 
	scale? The evidence is mixed. In 1 study, telemonitoring of hypertension led 
	to larger reductions in blood pressure than did standard care. Another for heart
	failure did not.
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	STRATEGIC RELATIONSHIPS

	Subcategory: Licensing Deals

	Partnering for Success...and Survival
	          Ted Agres Drug Discovery & Development (06-Dec-11)
	Biotechs will find it harder to obtain additional financing if their products are 
	tied up in exclusive deals with other partners. Big Pharma has tended to favor 
	partnering for products that have already been through at least some early 
	stage testing.
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Copyright 2012, Technology Management Associates, Inc. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.